微生物发酵中草药的研究现状

中草药作为天然传统药物,具有纯天然、无药残、无抗药性和毒副作用小等特点,在临床医疗和日常保健中被广泛使用.微生物发酵中草药过程中,中草药经微生物产生的酶作用后,细胞壁中的纤维素、木质素等物质被降解,其活性成分得以释放;中草药活性成分酶解为小分子物质,增强药效以利于机体消化吸收.部分中草药经发酵可以降低其毒性,减少毒副作...

Research status of microbial fermentation of Chinese herbal medicine

As a natural traditional medicine, Chinese herbal medicine is widely used in clinical medicine and daily health care because of its characteristics of pure nature, no drug residue and resistance, and little toxic and side effects. In the process of microbial fermentation of Chinese herbal medicine, the cellulose and lignin other substances in the cell-wall are degraded by enzymes produced by microorganisms, and the active components are released; The active components of Chinese herbal medicine are enzymolyzed into substances with small molecular, which could enhance the efficacy and be conducive to digestion and absorption of the body. After fermentation, some Chinese herbal medicines could reduce the toxicity and side effects and even produce new active substances. Meanwhile, some ingredients in Chinese herbs can promote the growth and reproduction of microorganisms. It can be seen that Chinese herbal medicine and microorganism have synergistic effect and complement each other. In this paper, the advantages, common microorganisms, application status, existing problems and key factors of fermentation of Chinese herbal medicine were reviewed, and the application prospect of fermentation of Chinese herbal medicine was prospected. It is believed that with the maturity of fermentation technology and the modern development of Chinese herbal medicine, the microbial fermentation of Chinese herbal medicine will have a broader development potential and application value in the future.