植物类病变突变体的诱发与突变机制

植物类病变突变体（lesion mimic mutant，LMM）是在无明显逆境或病原物侵染时，植物自发地形成类似病斑的一类突变体。它涉及到细胞程序性死亡（programmed cell death，PCD），往往能提高植物的抗病能力。因此，它对于揭示植物抗病反应机制，增加植物的广谱抗性具有重要意义。现就植物类病变突变体的诱发与表型特点、突变基因的分子定位与克隆及类病变表型的形成机制研究进展作一简要综述，以期为植物细胞程序性死亡机制和抗病分子作用机制研究提供有益的信息。

Induction and Mutation Mechanism of Plant Lesion Mimic Mutants

Plant lesion mimic mutants develop spontaneous lesions that resemble disease symptoms in the absence of pathogen and stress attack. The mutated genes of the lesion mimic mutation have been shown to involve in programmed cell death, which leads to enhanced disease resistance to multiple pathogens. Therefore, the research on plant lesion mimic mutants plays an important role in revealing the mechanisms of disease resistance response and enhancing the resistance spectrum of plant. The paper briefly reviewed the induction of lesion mimic mutants in plants, molecular mapping and cloning of mutated genes and the mechanism of lesion phenotype formation, which can provide the interest information for the research on the mechanisms of programmed cell death and plant disease resistance.