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HIV-Associated Kaposi Sarcoma and Gender
Affiliation:1. Department of Geography, School of Earth Sciences, China University of Geosciences, Wuhan 430074, China;2. State Key Laboratory of Biogeology and Environmental Geology, China University of Geosciences, Wuhan 430074, China;3. Canik Basari University, Faculty of Architecture and Engineering, Civil Engineering Department, Samsun, Turkey;4. Department of Water Engineering, Shahid Bahonar University of Kerman, Kerman, Iran;5. State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry (LAPC), Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China;6. State Key Laboratory of Information Engineering in Surveying, Mapping and Remote Sensingó, Wuhan University, Wuhan, Hubei Province 430079, China;7. Collaborative Innovation Center for Geospatial Technology, Wuhan 430079, China;1. Department of Occupational and Environmental Epidemiology, Bavarian Health and Food Safety Authority, Germany;2. Department of Social Epidemiology, Institute for Public Health and Nursing Research, University of Bremen, Germany;1. Department of Obstetrics, Gynecology, Perinatology and Reproduction, I.M. Sechenov First Moscow State Medical University, Oparin st. 4, 117997 Moscow, Russia;2. Federal State Budget Institution “Research Center for Obstetrics, Gynecology and Perinatology” of Ministry of Healthcare of the Russian Federation, Oparin st. 4, 117997 Moscow, Russia;3. Department of Clinical Andrology, Federal State Budget Institution Peoples'' Friendship University of Russia, Stavropol''skaya st. 23, 109386 Moscow, Russia;1. Division of Chronic Disease Epidemiology, Institute for Epidemiology, Biostatistics and Prevention, University of Zurich, Zurich, Switzerland;2. Cancer Registry Zurich and Zug, University Hospital Zurich, Zurich, Switzerland;3. Division of Cancer Studies, Translational Oncology & Urology Research (TOUR), King’s College London, London, United Kingdom
Abstract:Background: Cancer in individuals living with HIV and AIDS is a common source of morbidity and mortality, especially in the underdeveloped world. As antiretrovirals are distributed with greater equity across the globe, individuals with HIV and AIDS are living longer and developing malignancies, as opposed to other opportunistic infections.Objective: This article reviews the gender differences in studies of AIDS-associated cancers, examining factors related to transmission, treatment, and outcome.Methods: MEDLINE, PubMed, Ovid, conference proceedings, and abstract books were searched from 1983 onward for English-language publications and data on gender differences related to AIDS-associated cancers. Relevant trials were similarly reviewed. The search terms used were women or gender, cancer or tumor or malignancy, lymphoma or Kaposi, and HIV or AIDS.Results: We found that studies in established market economies have focused predominantly on men, although a wider view suggests that the rapidly growing rates of HIV infection among women should prompt specific oncologic challenges.Conclusion: Immunosuppression-induced malignancies in women, Kaposi sarcoma in particular, are likely to represent a global issue in the future. (Gend Med..
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