Cultivation of Aspergillus niger in a pilot plant external-loop air-lift bioreactor |
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Authors: | P. G uszcz,H. Michalski |
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Affiliation: | Faculty of Process and Environmental Engineering, Bioprocess Engineering Section, Technical University of Łódź, Wólczańska 175, 90-924 Łódź, Poland |
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Abstract: | Abstract: Changes of the main hydrodynamic and oxygen transfer parameters during Aspergillus niger cultivation in an external-loop air-lift bioreactor of 200 dm3 operating capacity were investigated. The final average concentrations of biomass and citric acid obtained in batch fermentations were about 17 g 1-1 and 90 g 1-1, respectively. Significant influence of the increasing biomass concentration on the rheological properties of the broth and operating parameters was found. Volumetric oxygen transfer coefficient. k L a , was found to be dependent on the apparent viscosity of the broth with an exponent of -0.984. |
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Keywords: | Air-lift bioreactor Citric acid fermentation Hydrodynamics Mass transfer |
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