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Inhibitory effect of penicillin on spore-specific functions inBacillus polymyxa 2459
Authors:Anil K Goel  Kunthala Jayaraman
Institution:(1) Department of Molecular Biology, School of Biological Sciences, Madurai Kamaraj University, 625 021 Madurai
Abstract:Penicillin at concentrations non-inhibitory to the vegetative growth was found to inhibit sporulation inBacillus polymyxa 2459. The effect of penicillin was shown to be at the level of spore-specific mucopeptide synthesis. Penicillin had no effect on the early events such as DNA and protein synthesis in sporogenesis The sensitive period of inhibition was between T0 to T2 hours of sporulation.
Keywords:Spore-specific functions  spore-specific mucopeptide  sporulation            Bacillus polymyxa 2459
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