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Tiny keratotic brown lesions on the interdigital web between the toes of a healthy man caused by Curvularia species infection and a review of cutaneous Curvularia infections
Authors:Makoto Yanagihara  Masako Kawasaki  Hiroshi Ishizaki  Kazushi Anzawa  Shun-ichi Udagawa  Takashi Mochizuki  Yukio Sato  Nobuyuki Tachikawa  Hiroyoshi Hanakawa
Institution:(1) Department of Dermatology, Shinseikai Toyama Hospital, 89-10 Shimowaka, Imizu 939-0243, Japan;(2) Department of Dermatology, Kanazawa Medical University, Uchinada Ishikawa, 920-0293, Japan;(3) Division of Dermatomycology, Research Center for Medical Science, Kanazawa Medical University, Uchinada Ishikawa, 920-0293, Japan;(4) Tama Laboratory, Japan Food Research Laboratories, 6-11-10 Nagayama, Tama Tokyo, 206-0025, Japan;(5) Faculty of Engineering, Toyama Prefectural University, Imizu Toyama, 939-0398, Japan
Abstract:A 74-year-old healthy Japanese man had noticed an itchy lesion with two tiny thick brown scales on the fourth interdigital web of his right foot 3 months earlier. The brown fungus isolated from the scales had demonstrated brown, ellipsoidal, obovoid or clavate, 3-septate conidia. Morphologically, the fungus was identified as Curvularia sp., and was differentiated from other human pathogenic species of the genus, such as C. lunata, C. pallescens, C. trifolii, C. clavata, and C. brachyspora, by molecular analysis based on the DNA sequence data. The fungus grows well on keratotic materials (hairs, nails, and callus), which indicates that it might have the ability to infect the skin surface.
Keywords:Phaeohyphomycosis  SEM  Skin infection
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