T- and B-lymphocytes of guinea pigs sensitized to ragweed pollen]

Functional activity of T and B lymphocytes in guinea pigs sensitized with common ragweed pollen was investigated. The content of T and B rosette-forming cells (T RFC and B RFC) was studied in guinea pigs following sensitization with common ragweed pollen. It was shown that the amount of B RFC in the regional lymph nodes at the early period of sensitization was over 4 times greater than that of the B RFC in normal animals. Functional capacity of T cells during the sensitization determined in the rosette-formation test altered less than the analogous capacity of B cells.