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An Intramolecular Interaction of UHRF1 Reveals Dual Control for Its Histone Association
Authors:Linfeng Gao  Xiao-Feng Tan  Shen Zhang  Tianchen Wu  Zhi-Min Zhang  Hui-wang Ai  Jikui Song
Institution:1. Environmental Toxicology Graduate Program, University of California, Riverside, CA 92521, USA;2. Department of Biochemistry, University of California, Riverside, CA 92521, USA;3. Department of Chemistry, University of California, Riverside, CA 92521, USA;4. Center for Membrane and Cell Physiology, Department of Molecular Physiology and Biological Physics, and Department of Chemistry, University of Virginia, Charlottesville, VA 22908, USA
Abstract:
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  • Keywords:DNA methylation  UHRF1  allosteric regulation  epigenetics  histone modification  autoinhibition  tandem Tudor domain
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