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Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling
Authors:Kate L. White  Matthew T. Eddy  Zhan-Guo Gao  Gye Won Han  Tiffany Lian  Alexander Deary  Nilkanth Patel  Kenneth A. Jacobson  Vsevolod Katritch  Raymond C. Stevens
Affiliation:1. Departments of Biological Sciences and Chemistry, Bridge Institute, USC Michelson Center, University of Southern California, 1002 West Childs Way, Los Angeles, CA 90089, USA;2. Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
Abstract:
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  • Keywords:GPCR  cell signaling  adenosine receptor  allosteric modulators  crystallography  structural biology  sodium binding
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