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Solution Structures of Engineered Vault Particles
Authors:Ke Ding  Xing Zhang  Jan Mrazek  Valerie A Kickhoefer  Mason Lai  Hwee L Ng  Otto O Yang  Leonard H Rome  Z Hong Zhou
Institution:1. Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA;2. California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA;3. Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA;4. Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA;5. Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA;6. AIDS Healthcare Foundation, Los Angeles, CA 90028, USA
Abstract:
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  • Keywords:cryo-EM  nanoparticle engineering  structural dynamics  drug delivery  vaccine design  human immunodeficiency virus (HIV)  protein design  single-particle analysis  imaging  cellular organelle
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