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Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
Authors:Yan Li  Zhenzhen Zhang  Wint Wint Phoo  Ying Ru Loh  Rong Li  Hai Yan Yang  Anna E Jansson  Jeffrey Hill  Thomas H Keller  Kassoum Nacro  Dahai Luo  CongBao Kang
Institution:2. Lee Kong Chian School of Medicine, Nanyang Technological University, EMB 03-07, 59 Nanyang Drive, Singapore 636921, Singapore;3. NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 Nanyang Drive, Singapore 636921, Singapore;4. School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 636921, Singapore
Abstract:
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  • Keywords:Zika virus  protease  drug discovery  protein dynamics  structure  protease inhibitor
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