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Conformational Plasticity of the Immunoglobulin Fc Domain in Solution
Authors:Soumya G. Remesh  Anthony A. Armstrong  Andrew D. Mahan  Jinquan Luo  Michal Hammel
Affiliation:1. Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA;2. Janssen BioTherapeutics, Janssen R&D, LLC, Spring House, PA 19477, USA
Abstract:
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  • Keywords:immunoglobulin G antibody (IgG)  fragment crystallizable (Fc) region  small angle X-ray scattering  SAXS  conformational flexibility  glycoprotein  rigid body modeling  BILBOMD
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