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Toward an Ensemble View of Chromatosome Structure: A Paradigm Shift from One to Many
Authors:Mehmet Ali Öztürk  Vlad Cojocaru  Rebecca C Wade
Institution:1. Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies (HITS), 69118 Heidelberg, Germany;2. The Hartmut Hoffmann-Berling International Graduate School of Molecular and Cellular Biology (HBIGS), Heidelberg University, 69120 Heidelberg, Germany;3. Computational Structural Biology Laboratory, Department of Cellular and Developmental Biology, Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany;4. Center for Multiscale Theory and Computation, Westfälische Wilhelms University, 48149 Münster, Germany;5. Center for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, 69120 Heidelberg, Germany;6. Interdisciplinary Center for Scientific Computing (IWR), 69120 Heidelberg, Germany
Abstract:
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  • Keywords:linker histone  nucleosome  chromatosome  chromatin  macromolecular structure  macromolecular dynamics  X-ray crystallography  NMR  cryo-EM
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