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Iso-antibodies to red cell antigens in pigs' sera. 1. Iso-immunisation of pregnancy in sows |
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| Authors: | K A Linklater |
| Institution: | Department of Animal Health, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Veterinary Field Station, Easter Bush, Roslin, Midlothian, Scotland |
| Abstract: | It has been demonstrated that iso-immunisation of sows by foetal red cell antigens can occur. Four sows were shown to produce iso-antibodies to the blood group factors Ea and Kb, after giving birth to Ea-positive and Kb-positive piglets, respectively. They did not produce the antibodies after giving birth to only Ea-negative and Kb-negative piglets, respectively. Two Ea-negative gilts and a further Ea-negative sow, all of which had no evidence of red cell iso-antibodies in their sera were mated to an Ea-positive boar. Anti-Ea was detected in the sera of two of them for the first time after the subsequent parturition; the third remained negative. Complete and reliable life histories of all these animals were available. There were no previous injections of pig red cells in any form. |
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