Unusual stilbenoids and a stilbenolignan from seeds of Syagrus romanzoffiana |
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Authors: | Sio-Hong Lam |
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Institution: | School of Pharmacy, College of Medicine, National Taiwan University, Taipei 10051, Taiwan, ROC |
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Abstract: | Stilbenoids, syagrusins A-B (1-2), and a stilbenolignan, 5-hydroxyaiphanol (3), along with three known phenylpropanoids (4-6), were isolated from seeds of Syagrus romanzoffiana. Compounds 1 and 2 possess unusual 1,4,4a,9a-tetrahydrofluoren-9-one and bicyclo3.3.0]octanedione skeletons, respectively, whereas compound 3 is a stilbenolignan belonging to a very rare structural class of plant secondary metabolites. Their structures were elucidated by spectroscopic analyses. Compounds 1-3 exhibited moderate inhibitory activity against α-glucosidase with IC50 values of 16.9 μM (1), 23.7 μM (2) and 12.8 μM (3), respectively. |
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Keywords: | Syagrus romanzoffiana Arecaceae α-Glucosidase inhibitor Stilbenoids Syagrusins A-B Stilbenolignan 5-Hydroxyaiphanol |
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