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Computational study of biomechanical drivers of renal cystogenesis |
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| Authors: | Ateshian Gerard A Spack Katherine A Hone James C Azeloglu Evren U Gusella G Luca |
| Institution: | 1.Department of Mechanical Engineering, Columbia University, New York, NY, USA ;2.Department of Biomedical Engineering, Columbia University, New York, NY, USA ;3.Department of Medicine, Division of Nephrology, Mount Sinai School of Medicine, New York, NY, USA ;4.Department of Pharmacological Sciences, Mount Sinai School of Medicine, New York, NY, USA ; |
| Abstract: | Biomechanics and Modeling in Mechanobiology - Renal cystogenesis is the pathological hallmark of autosomal dominant polycystic kidney disease, caused by PKD1 and PKD2 mutations. The formation of... |
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