REST acts through multiple deacetylase complexes |
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Authors: | Griffith E C Cowan C W Greenberg M E |
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Institution: | Division of Neuroscience, Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. |
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Abstract: | The RE1 binding silencer protein REST represses neuronal-specific gene expression in nonneuronal cell types. In this issue of Neuron, Ballas et al. show that REST inhibits gene expression via the recruitment of multiple histone deacetylase complexes. |
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