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PDX1 Deficiency Causes Mitochondrial Dysfunction and Defective Insulin Secretion through TFAM Suppression
Authors:Benoit R Gauthier  Andreas Wiederkehr  Mathurin Baqui  Chunhua Dai  Alvin C Powers  Julie Kerr-Conte  Franois Pattou  Raymond J MacDonald  Jorge Ferrer  Claes B Wollheim
Institution:1 Department of Cell Physiology and Metabolism, University of Geneva, Geneva, Switzerland;2 Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA;3 VA Tennessee Valley Healthcare System, Nashville, TN 37212-2637, USA;4 INSERM U859, University of Lille, Northern France, Lille University Hospital, Lille, France;5 Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;6 Hospital Clinic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, CIBER de Diabetes y Enfermedades Metabólicas Asociadas Barcelona, Spain
Abstract:
Keywords:HUMDISEASE
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