Effects of ICI 182780 on estrogen receptor expression,fluid absorption and sperm motility in the epididymis of the bonnet monkey |
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| Authors: | Deshpande?Shayu,CS?Chennakesava,Rama?Soundarajan,A?Jagannadha?Rao mailto:ajrao@biochem.iisc.ernet.in" title=" ajrao@biochem.iisc.ernet.in" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author |
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| Affiliation: | (1) Department of Biochemistry, Indian Institute of Science, 560012 Bangalore, India;(2) Department of Medicine, Division of Nephrology, University of California San Francisco, 94143 SanFrancisc, USA;(3) Department of Clinical Research, University of Bern, 120 Tiefenaustrasse 3004, Bern, Switzerland |
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| Abstract: | ![]()
Background The importance of estrogen in regulation of fluid absorption and sperm maturation in the rodent epididymis has been established from studies on estrogen receptor-alpha knockout mice. However, functional studies on the role of estrogen in primate epididymis have been few. The main objective of this study was therefore to extend these observations and systematically analyze the presence and function of estrogen receptors in modulating the function of the primate epididymis, using the bonnet monkey (Macaca radiata) as a model system. |
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