Abstract: | In experiments on white mice the immunogenic potency of two variants of combined vaccines prepared from strains of opportunistic bacteria was compared with that of monovaccines used as the components of the combined vaccines. All the vaccines under study were found highly immunogenic. Decrease of monovaccine share in the combined vaccine did not reduce the immunogenic potency to any of the strains. An 8- to 16-fold increase in the level of specific antibodies in the colostric lactosera of cows immunized with combined vaccines was observed, and the survival rate of newborn calves increased 3- to 4-fold. |