Identification of DysI, the immunity factor of the streptococcal bacteriocin dysgalacticin |
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| Authors: | Swe Pearl M Heng Nicholas C K Cook Gregory M Tagg John R Jack Ralph W |
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| Institution: | Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand. |
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| Abstract: | DysI is identified as the protein that confers specific immunity to dysgalacticin, a plasmid-encoded streptococcal bacteriocin. dysI is transcribed as part of the copG-repB-dysI replication-associated operon. DysI appears to function at the membrane level to prevent the inhibitory effects of dysgalacticin on glucose transport, membrane integrity, and intracellular ATP content. |
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