Studies on the energy metabolism of opossum Didelphis virginiana erythrocytes--II. Comparative aspects of 2-deoxy-D-glucose catabolism in opossum and human red cells in vitro |
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Authors: | N C Bethlenfalvay J E Lima T L Waldrup E Chadwick I Stewart |
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Affiliation: | Department of Primary Care, Fitzsimons Army Medical Center, Aurora, CO 80045-5000. |
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Abstract: | 1. G-6-P, F-6-P, F-1, 6-P, DHAP and GA-3-P in opossum erythrocytes were found at levels above those reported in human red cells. 2. About 1% of the radioactivity provided as [1-14C] DOG to red cells of both species was recovered as 14CO2 in 1 hr. 3. Unlike [1-14C] DOG, radiochromatography of extracts of cells incubated DOG revealed two diffusible radiolabelled compounds in the supernatant of cell suspensions. 4. The catabolism of DOG was quantitatively and qualitatively similar in opossum and human erythrocytes under the conditions of this study. |
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