Crystallographic data on a complete kappa-type human Bence-Jones protein. |
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Authors: | M Schiffer F A Westholm N Panagiotopoulos A Solomon |
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Affiliation: | Division of Biological and Medical Research Argonne National Laboratory Argonne, IL, 60439, U.S.A.;Memorial Research Center University of Tennessee Center for the Health Sciences Knoxville, TN, 37920, U.S.A. |
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Abstract: | A complete human κ-type Bence—Jones protein (Fin) has been isolated and crystallized. Immunochemical and physicochemical characterization of protein Fin indicates that it is of the κ-chain subgroup, κII, and that it consists of two non-covalently bound intact monomers having a molecular weight of ~23,000 Crystals of Bence—Jones protein Fin obtained from ammonium sulfate solutions have the orthorhombic space group P212121 with cell dimensions . The asymmetric unit consists of a dimer of molecular weight ~46,000. |
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Keywords: | Author to whom all correspondence should be addressed. |
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