L-nucleosides containing modified nucleobases |
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| Authors: | Seela Frank Lin W Kazimierczuk Z Rosemeyer H Glaron V Peng X He Y Ming X Andrzejewska M Gorska A Zhang X Eickmeier H La Colla P |
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| Affiliation: | Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universit?t Osnabrück, Germany. |
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| Abstract: | The synthesis of base modified L-nucleosides is described with pyrrolo[2,3-d]pyrimidines, pyrazolo[3,4-d]pyrimidines, benzimidazoles, and imidazo[1,2-a]-s-triazines as nucleobases. The conformation of the nucleosides is studied and the antiviral activity is evaluated. |
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