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Novel synthesis of carbocyclic nucleosides from 2-azabicyclo[2.2.1]heptanes via the reductive N2-C3 cleavage reaction as a key step |
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| Authors: | N Katagiri M Muto C Kaneko |
| Institution: | Pharmaceutical Institute, Tohoku University, Sendai, Japan. |
| Abstract: | Carbocyclic ribofuranosyl and arabinofuranosyl pyrimidine nucleosides were synthesized stereoselectively from 2-azabicyclo2.2.1]hept-5-en-3-one via NaBH4 promoted C-N bond cleavage reaction as a key step. |
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