Human carbonic anhydrases. VII. A new C type isozyme in erythrocytes of American Negroes

An unusual erythrocyte carbonic anhydrase C type isozyme tentatively designated as H has been found in American Negroes. It has an electrophoretic mobility near that of carbonic anhydrase B. In about 18% of the individuals studied the H isozyme replaces half of the normal C isozyme, and in about 1% of this population only the H isozyme is present.This work was supported in part by Grant CA-01786 from the United States Public Health Service. One of us (M.J.M.) is a recipient of a National Institutes of Health predoctoral traineeship on U.S. Public Health Training Grant No. 5-T01-GM0125-05 to the Department of Anthropology.