| 茵陈保肝活性部位的初步筛选研究 |
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| 引用本文： | 周立,万丽,叶娉,王敏,王凌.茵陈保肝活性部位的初步筛选研究[J].现代生物医学进展,2008,8(1):114-115. |
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| 作者姓名： | 周立 万丽 叶娉 王敏 王凌 |
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| 作者单位： | 成都中医药大学,成都,610075 |
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| 摘 要： | 目的:筛选茵陈发挥保肝作用的有效部位.方法:用系统溶剂分离法将茵陈分离成极性不同的组分.采用四氯化碳(CCl4)致小鼠急性肝损伤模型,按赖氏法测定小鼠血清中AST,ALT的活性.结果:茵陈的三氯甲烷提取物能明显降低CCl4引起的AST,ALT增高.结论:茵陈三氯甲烷提取部位为其发挥保肝作用的有效部位.
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| 关 键 词： | 茵陈 保肝作用 活性部位 茵陈 保肝活性部位 筛选研究 Scoparia Artemisia Active Screening 提取部位 提取物 三氯甲烷 结果 小鼠血清 测定 赖氏法 肝损伤模型 急性 四氯化碳 组分 分离法 系统溶剂 |
| 文章编号： | 1673-6273（2008）01-0114-02 |
| 收稿时间： | 2007-10-02 |
| 修稿时间： | 2007-10-31 |
Preliminary Screening of Active Part of Artemisia Scoparia Waldst.et Kit.in the Liver Protection |
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| ZHOU Li,WAN Li,YE Ping,WANG Min,WANG Ling.Preliminary Screening of Active Part of Artemisia Scoparia Waldst.et Kit.in the Liver Protection[J].Progress in Modern Biomedicine,2008,8(1):114-115. |
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| Authors: | ZHOU Li WAN Li YE Ping WANG Min WANG Ling |
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| Abstract: | Objective:To screen the effective fraction with liver protection activity from Artemisia scoparia Waldst.et Kit.Meth- ods:Fractions of Artemisia scoparia Waldst.et Kit.with different polarities were obtained from a serious of extraction solutions.The ac- tivities of AST and ALT were measured in liver injury mouse model induced by carbon tetrachloride(CCl_4).Results:In this experiment, chloroform extract of Arternisia scoparia Waldst.et Kit.can significantly decrease the serum transaminase(ALT,AST)activities in liver injury mouse model induced by carbon tetrachloride.Conclusion:The chloroform extract is the effective part of Artemisia scoparia Waldst.et Kit.for liver protection. |
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| Keywords: | Artemisia scoparia Waldst et Kit Liver protection Active fraction |
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