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The effect of electrolytes on the 2, 4-dinitrophenol activated ATPase of rat liver mitochondria
Authors:R Cereijo-Santaló
Affiliation:Research Department, The New Mount Sinai Hospital, Toronto 2, Ontario, Canada
Abstract:The activation of mitochondrial ATPase by DNP has been studied in different media (sucrose, choline-Cl, Tris-Cl, LiCl, NaCl, KCl, and RbCl). With fresh mitochondria the addition of DNP plus valinomycin inhibits ATPase activity in all media except in those containing potassium or rubidium, while the addition of DNP plus gramicidin inhibits ATPase only in sucrose, choline and Tris media.
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