Effect of a single ethanol administration on the permeability of the hemato-encephalic barrier for 14C-tyrosine, 14C-DOPA and horseradish peroxidase |
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| Authors: | Iu V Burov S A Borisenko K Kiianmaa J Lehtosalo P Mannisto |
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| Abstract: | Single injection of ethanol at a dose of 2 and 4 g/kg has been shown to increase blood-brain barrier penetration for peripherally administered 14C-tyrosine and 14C-DOPA. No changes in blood-brain barrier penetration for horseradish peroxidase has been found. Acute effect of ethanol on blood-brain barrier systems of specific and nonspecific transport is discussed. |
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