Integration of Simian Virus 40 Deoxyribonucleic Acid into the Deoxyribonucleic Acid of Primary Infected Chinese Hamster Cells |
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| Authors: | K. Hirai J. Lehman V. Defendi |
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| Affiliation: | The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania 19104 |
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| Abstract: | Simian virus 40 deoxyribonucleic acid (DNA) became associated in an alkaline-stable form with the DNA of Chinese hamster embryo cells at 15 to 20 hr post-infection, at the time when cell DNA synthesis and T antigen were induced. The integration process was not inhibited by d-arabinosyl cytosine and was only partially inhibited by cycloheximide. |
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