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Cucurbitacins from Bacopa monnieri
Authors:Bhandari Pamita  Kumar Neeraj  Singh Bikram  Kaul Vijay K
Institution:Natural Plant Products Division, Institute of Himalayan Bioresource Technology, Palampur 176 061, Himachal Pradesh, India.
Abstract:Four cucurbitacins, bacobitacin A-D (1-4) as well as, a known cytotoxic, cucurbitacin E (5) together with three known phenylethanoid glycosides, monnieraside I, III and plantioside B were isolated form the aerial part of Bacopa monnieri. Their structures were elucidated on the basis of extensive spectroscopic investigations (1D, 2D NMR and ESI-QTOF-MS/MS). This is the first report on the characterization of cucurbitacins in B. monnieri.
Keywords:Bacopa monnieri  Scrophulariaceae  Cucurbitacins  Bacobitacin A-D  ESI-QTOF-MS
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