Structural studies of the Shigella flexneri variant X, type 5 a and type 5 b O-antigens. |
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Authors: | L Kenne B Lindberg K Petersson E Katzenellenbogen E Romanowska |
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Abstract: | Previous studies of different Shigella flexneri O-antigens indicate that their O-specific region is composed of oligosaccharide repeating units containing a basic tetrasaccharide structure, to which alpha-D-glucopyranosyl groups and O-acetyl groups may be attached to different positions. Structural studies of O-antigens from variant X, type 5a and type 5b lend further support to this assumption. These antigens contain terminal alpha-D-glucopyranosyl groups, one each per repeating unit in X and 5a, two in 5b. The location of these groups in the repeating unit has been determined. |
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