The MRNA expression of the human 1,25-dihydroxyvitamin D3 receptor and the c-myc protooncogene in cultured human keratinocytes |
| |
| Authors: | Nancy M. Hanafin Kelly Scott Persons Michael F. Holick |
| |
| Affiliation: | (1) Vitamin D, Skin, and Bone Research Laboratory, Boston University School of Medicine and Boston City Hospital, 80 East Concord Street, M-1013, 02118 Boston, Massachusetts |
| |
| Abstract: | Summary The human vitamin D receptor mRNA expression in preconfluent human cultured keratinocytes was upregulated by treatment of these cells with 10−8 M 1,25(OH)2D3 for 24 hours. Additionally, human c-myc mRNA expression was decreased in a dose dependent manner by 1,25(OH)2D3 in both preconfluent and confluent cultured human keratinocytes. |
| |
| Keywords: | skin VDR c-myc keratinocytes 1,25-dihydroxyvitamin D3 |
| 本文献已被 SpringerLink 等数据库收录！ |
|
