Ultrastructural changes in the cells of bone marrow capillaries in chronic lead exposure

Prolonged influence of lead on the laboratory white rats was studied. The interchange of the "light" and "dark" endothelial cells in the bone marrow capillaries, pseudomyelination of mitochondria, periendothelial space extension, more dense or loose basement layer and clasmatosis in the adventitial cells of sinusoids were observed. These alterations were observed in both adult and newborn rats whose parents were influenced by lead before the coupling.