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Identified vertebrate neurons that differ in axonal projection develop together
Authors:B Mendelson  C B Kimmel
Institution:1. Dept. Cell Biology and Pathology, IBSAL-Institute of Neurosciences of Castilla and León University of Salamanca Salamanca, Spain;2. Institute of Clinical Anatomy and Cell Analysis University of Tübingen Tübingen, Germany;1. Division of Cellular and Molecular Neurobiology, Zoological Institute, Braunschweig University of Technology, 38106 Braunschweig, Germany;2. Department of Biotechnology and Bioinformatics, Braunschweig University of Technology, Braunschweig 38106, Germany;1. Department of Genetics, Development, and Cell Biology, Iowa State University, Ames, IA 50011, United States;2. Neuroscience Program, United States;3. Department of Animal Science, Iowa State University, Ames, IA 50011, United States;4. Genetics and Genomics Program, United States
Abstract:The development of identified reticulospinal neurons of the zebrafish (Brachydanio rerio) was studied in order to learn if cell specific differences in axonal projection are correlated with cell specific differences in time of neuronal development. We examined the development of individually known reticulospinal neurons that are located in close proximity in the hindbrain but that project axons to targets on opposite sides of the spinal cord. We observed that these identified neurons are generated together, and that their axons first arrive in the spinal cord together. We suggest that the selection of different axonal pathways by these neurons does not depend on the time that they develop.
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