Genetic polymorphism of alpha-1-antitrypsin in macaque species |
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| Authors: | E Samilchuk S Sarsaniya |
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| Institution: | (1) Institute of Pulmonology, Moscow;(2) Present address: Kuwait Medical Genetics Center, P. O. Box 31121, 80901 Sulibikhat, Kuwait |
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| Abstract: | Thirty-two phenotypes of alpha-1-antitrypsin (al-AT) controlled by 18 codominant alleles of PImac locus were identified by isoelectric focusing in 1.121 macaques of nine species. In terms of al-AT polymorphism macaque species
vary markedly from nearly monomorphic (Macaca mulatta, M. arctoides) to highly polymorphic (M. nemestrina, M. fascicularis). Only 4 of 18 PImac alleles are common for two or more macaque species, the rest of the alleles are species-specific. |
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| Keywords: | Alpha-1-antitrypsin PI-system Macaque |
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