Distribution of specific proteins in the salivary gland lobes of Culicidae and their relation to age and blood sucking

Specific proteins are produced in different parts of the salivary glands of female Anopheles and Culex. In both species there are concentrated low molecular weight proteins in the median lobes and proteins in the mol. wt range 25,000–60,000 in the distal parts of the lateral lobes. These proteins are not identical in the two species. In the proximal parts of the lateral lobe there are only small amounts of protein in addition to an unknown high molecular weight substance. At the time of blood-sucking 15–35% of soluble gland proteins are injected with the saliva into the host animal, the proteins from the median lobes and the proximal part of the lateral lobes being released in greater quantities than the proteins from the distal parts of the lateral lobes. The typical gland proteins are only extractable in low concentrations from the salivary glands of the newly-hatched adult mosquito, they increase up to the 7th day of the adult development and are stored in the glands.