Computational structural analysis of protein interactions and networks |
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Authors: | Hooda Yogesh Kim Philip M |
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Institution: | Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada. |
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Abstract: | Protein interactions have been at the focus of computational biology in recent years. In particular, interest has come from two different communities--structural and systems biology. Here, we will discuss key systems and structural biology methods that have been used for analysis and prediction of protein-protein interactions and the insight these approaches have provided on the nature and organization of protein-protein interactions inside cells. |
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Keywords: | Bioinformatics Docking Machine learning Peptide recognition modules Protein interaction networks Protein interfaces |
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