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Acute treatment of migraine. Breaking the paradigm of monotherapy
Authors:Email author" target="_blank">Abouch?Valenty?KrymchantowskiEmail author
Institution:(1) Department of Neurology, Universidade Federal Fluminense, Rio de Janeiro, Brazil;(2) Headache Outpatient Service, Instituto de Neurologia Deolindo Couto, Rio de Janeiro, Brazil;(3) Headache Center of Rio, Rio de Janeiro, Brazil
Abstract:

Background  

Migraine is a highly prevalent disorder. The disability provoked by its attacks results in suffering as well as considerable economic and social losses. The objective of migraine acute treatment is to restore the patient to normal function as quickly and consistently as possible. There are numerous drugs available for this purpose and despite recent advances in the understanding of the mechanisms and different biological systems involved in migraine attacks, with the development of specific 5-HT agonists known as triptans, current options for acute migraine still stand below the ideal.
Keywords:
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