Antimetabolites in the treatment of arthritis: current status of the use of antimetabolites |
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Authors: | Dijkmans B A C Jansen G |
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Institution: | Department of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands. |
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Abstract: | Rheumatoid arthritis (RA) is an autoimmune disease characterized by a chronic inflammation of the synovial joints and infiltration of blood-derived cells. In daily practice rheumatologists use the antimetabolites methotrexate (MTX) and leflunomide for the treatment of patients with rheumatoid arthritis. The current clinical status (efficacy/toxicity) of these 2 antimetabolites in the treatment of RA will be discussed. |
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