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Complex genetic effect of B10.D2 (M504) (H-2dm1) mutation
Authors:Dagmar Iványi  Peter Démant
Institution:(1) Division of Genetics, Antoni van Leeuwenhoekhuis, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Abstract:Serological and capping experiments show that the strain B10.D2 (M504) carrying the mutant haplotypeH-2 dm1 has two molecules in the products of theD region: H-2Ddm1 and H-2Ldm1 which are detectable by anti-H-2.4 and by anti-H-2.28 sera, respectively. Both these molecules differ serologically from the H-2Dd and H-2Ld molecules of the original (nonmutant) strain B10.D2. A third molecule, different from H-2D and H-2L, was detected inH-2 d ,H-2 dm2 but not inH-2 dm1 products.
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