Complex genetic effect of B10.D2 (M504) (H-2dm1) mutation |
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Authors: | Dagmar Iványi Peter Démant |
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Institution: | (1) Division of Genetics, Antoni van Leeuwenhoekhuis, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands |
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Abstract: | Serological and capping experiments show that the strain B10.D2 (M504) carrying the mutant haplotypeH-2
dm1
has two molecules in the products of theD region: H-2Ddm1 and H-2Ldm1 which are detectable by anti-H-2.4 and by anti-H-2.28 sera, respectively. Both these molecules differ serologically from the H-2Dd and H-2Ld molecules of the original (nonmutant) strain B10.D2. A third molecule, different from H-2D and H-2L, was detected inH-2
d
,H-2
dm2
but not inH-2
dm1
products. |
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Keywords: | |
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