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Enantioselective synthesis of (+)-8-hydroxy-8-methylidarubicinone |
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| Authors: | Bourghli Laurance M S Stoodley R J |
| Institution: | Department of Organic Materials, Royal Scientific Society, Industrial Chemistry Center, Amman, Jordan. bourshli@rss.gov.jo |
| Abstract: | An asymmetric Diels-Alder reaction methodology was employed to construct the tetracyclic structure of the anthracyclinone. A five-step sequence was needed to furnish the target (+)-8-hydroxy-8-methylidarubicinone. |
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