S-100-like immunoreactivity in a planarian |
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Authors: | Dr Fabrizio Michetti Domenico Cocchia |
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Institution: | (1) Department of Anatomy, Università Cattolica S. Cuore, Rome, Italy;(2) Department of Anatomy, Università Cattolica S.Cuore, Via Pineta Sacchetti 644, 00168 Rome, Italy |
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Abstract: | Summary The presence of an S-100-like immunoreactivity was investigated in the planarian Dugesia gonocephala. By microcomplement fixation assay, measurable amounts of S-100-like immunoreactive material (0.11 g/mg soluble protein) were detected in planarian high-speed supernatants. The index of immunological dissimilarity between ox S-100 and planarian S-100-like immunoreactive material was higher than that previously calculated between ox S-100 and all the vertebrates tested. By the immunohistochemical PAP method, S-100-like immunoreactivity was only detectable in the cilia of the epidermal cells. Although the biological meaning of S-100-like immunoreactivity in planarian remains to be clarified, the present data introduce new perspectives into the investigation of S-100. |
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Keywords: | S-100-like immunoreactivity Planarian Microcomplement fixation PAP method |
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