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Genome analysis of bat adenovirus 2: indications of interspecies transmission
Authors:Kohl Claudia  Vidovszky Márton Z  Mühldorfer Kristin  Dabrowski Piotr Wojtek  Radonić Aleksandar  Nitsche Andreas  Wibbelt Gudrun  Kurth Andreas  Harrach Balázs
Affiliation:Robert Koch Institute, Centre for Biological Security, Berlin, Germany. KohlC@rki.de
Abstract:The genome of bat adenovirus 2 was sequenced and analyzed. It is similar in size (31,616 bp) to the genomes of bat adenovirus 3 and canine adenoviruses 1 and 2. These four viruses are monophyletic and share an identical genome organization, with one E3 gene and four E4 genes unique to this group among the mastadenoviruses. These findings suggest that canine adenoviruses may have originated by interspecies transfer of a vespertilionid bat adenovirus.
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