Prolonged production of tryptophan using immobilized bacteria |
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Authors: | Klara Dallmann Laszlo Orosz Béla Szajani |
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Institution: | (1) Institute for Molecular Genetics, Agricultural Biotechnology Center, POB 41, Godoll, H 2101, Hungary;(2) COVENT Industrial Venture Capital Investment Co Ltd, POB 335, H 1536, Hungary |
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Abstract: | Tryptophan production of a genetically modified E. coli strain possessing elevated tryptophan synthetase activity but sensitive to indole could be prolonged by the immobilization of cells in calcium alginate gel beads with a calculated half-life time of 12.2 days. |
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