Efficacy and safety of pregabalin 600 mg/d for treating painful diabetic peripheral neuropathy: A double-blind placebo-controlled trial |
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| Authors: | Joseph C Arezzo Julio Rosenstock Linda LaMoreaux Lynne Pauer |
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| Institution: | (1) Albert Einstein College of Medicine, New York, NY, USA;(2) Dallas Diabetes and Endocrine Center, Dallas, TX, USA;(3) Pfizer Global Research & Development, Ann Arbor, MI, USA |
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| Abstract: | Background Recent consensus guidelines recommend pregabalin as a first-tier treatment for painful diabetic peripheral neuropathy (DPN).
We evaluated the efficacy of pregabalin 600 mg/d (300 mg dosed BID) versus placebo for relieving DPN-associated neuropathic
pain, and assessed its safety using objective measures of nerve conduction (NC). |
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