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Drug resistance genomics of the antimalarial drug artemisinin |
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| Authors: | Winzeler Elizabeth A Manary Micah J |
| Affiliation: | 1. MRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, Cape Town, 7925, South Africa 2. DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Observatory, Cape Town, 7925, South Africa 3. Division of Medical Microbiology, Department of Clinical Laboratory Sciences, University of Cape Town, Anzio Road, Observatory, Cape Town, 7925, South Africa |
| Abstract: | Genomics research has enabled crucial insights into the adaptive evolution of Mycobacterium tuberculosis as an obligate human pathogen. Here, we highlight major recent advances and evaluate the potential for genomics approaches to inform tuberculosis control efforts in high-burden settings. |
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