Terpenoids and phenethyl glucosides from Hyssopus cuspidatus (Labiatae) |
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| Authors: | Furukawa Megumi Makino Mitsuko Ohkoshi Emika Uchiyama Taketo Fujimoto Yasuo |
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| Institution: | a College of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan
b Department of General Education, College of Humanities and Sciences, Nihon University, 3-25-40 Sakurajousui, Setagaya, Tokyo 156-8550, Japan |
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| Abstract: | Monoterpenoids (3 and 4), sesquiterpenoid (2), diterpenoid (1) and four phenethyl glucosides (5-8), together with fourteen known compounds, were isolated from the whole herb of Hyssopus cuspidatus. Their structures were determined by spectroscopic means. The abietane-type diterpenoids (1, 9, 10), rosmarinic acid (15) and salvigenin (17) inhibited leukotriene (LT) C4 secretion from primary alveolar cells of Wistar rats. |
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| Keywords: | Hyssopus cuspidatus Labiatae Abietane-type diterpenoids Eremophilane-type sesquiterpenoid Phenethyl glycosides Leukotriene |
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