Steroidal alkaloid saponins and steroidal saponins from Solanum surattense |
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Authors: | Lu Yuanyuan Luo Jianguang Kong Lingyi |
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Affiliation: | Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, PR China |
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Abstract: | A rare 16β-H steroidal alkaloid saponin (1), an avenacoside-type saponin (2), two steroidal saponins (4, 5), one revised-structure steroidal saponin (3) and six known compounds (6-11) were isolated from aerial parts of Solanum surattense Burm. f. Their structures were established on the basis of physical data, as well as by using spectroscopic (HRESIMS, 1D and 2D NMR), and chemical analysis methods. Compounds 1 and 11 showed cytotoxicity against A549 cell line with IC50 values of 20.3 and 15.7 μM, respectively. |
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Keywords: | Solanaceae Solanum surattense Steroidal alkaloid saponin Avenacoside-type saponin Steroidal saponin Cytotoxicity |
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