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Flypaper for parasites
Authors:Beverley Stephen M  Dobson Deborah E
Institution:Department of Molecular Microbiology, Washington University Medical School, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Abstract:In this issue, Kamhawi et al. (2004) describe the identification of an insect galectin as the receptor for the stage-specific Leishmania adhesin lipophosphoglycan (LPG). This interaction is critical for parasite survival in the midgut of its sand fly vector. The results open new avenues for studies of insect immunity, transmission binding vaccines, and host-parasite coevolution.
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